Yentreve is a medication that contains the active ingredient duloxetine. It is used to treat stress urinary incontinence (SUI) in women. Yentreve works by increasing the levels of certain chemicals in your brain that help control your bladder function. It is suitable for women who experience SUI, which is the unintentional loss of urine when you laugh, cough, sneeze, or exercise due to weak pelvic floor muscles.