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Premarin

Description

Premarin is a medication containing conjugated estrogens, which are a mixture of estrogen hormones. These hormones help relieve symptoms of menopause such as hot flashes, vaginal dryness, and irritation. Premarin works by supplementing the body with estrogen that it no longer produces in sufficient amounts. This medication is suitable for women experiencing menopausal symptoms like vaginal discomfort, itching, or burning.

Assessed by:

Dr Wouter Mol, General practitionerRegistration number: BIG: 9057675501Last checked: 17/03/2022 | Still valid
Dosage and usage
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You should take Premarin exactly as prescribed by your healthcare provider. The typical dose for menopausal symptoms is 0.3 mg to 1.25 mg daily, depending on your individual needs. Your doctor will determine the right dose for you. It's important to follow the prescribed dosage and not exceed it. If you miss a dose, take it as soon as you remember, but do not take a double dose to make up for the missed one. Premarin should be taken consistently at the same time each day to maintain hormone levels in your body.

What Premarin contains
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Premarin contains conjugated estrogens derived from natural sources like soybeans and yams. The tablets also include lactose monohydrate, microcrystalline cellulose, magnesium stearate, hypromellose, and more. Each tablet has a specific amount of conjugated estrogens, so make sure to check the dosage on your prescription label.

Side effects
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Common side effects of Premarin may include nausea, vomiting, breast tenderness, or headaches. Serious side effects that require immediate medical attention include chest pain, vision changes, unusual vaginal bleeding, or signs of a blood clot. If you experience any of these severe side effects, seek medical help promptly.

Precautions
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Do not use Premarin if you are pregnant, breastfeeding, have a history of certain cancers, or are allergic to any of its ingredients. Women with liver disease, a history of blood clots, or certain other health conditions should avoid using Premarin. It's important to discuss your medical history and current medications with your doctor before starting Premarin to ensure it is safe for you.

Sources
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Brazier, Yvette What you need to know about HRT (May 2017) Retrieved from https://www.medicalnewstoday.com/articles/181726.php

Irani, Shirin Consultant Gynaecologist Menopause (2019) Retrieved from https://www.bupa.co.uk/health- information/womens-health/menopause

NHS UK Hormone Replacement Therapy (July 2016) Retrieved from https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/

NHS UK Menopause Treatment (August 2018) Retrieved from https://www.nhs.uk/conditions/menopause/treatment/

Pfizer Pharmaceuticals Premarin (September 2018) Retrieved from http://labeling.pfizer.com/showlabeling.aspx?id=131#PI

Pfizer pharmaceuticals Premarin Package Leaflet (September 2016) Retrieved from https://www.medicines.org.uk/emc/files/pil.2900.pdf

Package leaflet

Read the package leaflet before use.

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