Kliovance is a medication that combines estradiol and norethisterone to help relieve symptoms of menopause such as hot flashes, night sweats, and vaginal dryness. Estradiol is a form of estrogen that helps replace the hormone that your body no longer produces in sufficient amounts during menopause. Norethisterone is a progestogen that works alongside estradiol to provide hormone replacement therapy. Kliovance is suitable for women experiencing menopausal symptoms and looking for relief.
You should take one Kliovance tablet daily, preferably at the same time each day. The tablets are taken continuously without a break between packs. Each pack contains 28 tablets. If you forget to take a tablet, take it as soon as you remember and continue as usual. If you are more than 12 hours late, skip the missed dose. The effects of Kliovance last throughout the 28-day cycle. If you experience any unusual symptoms or side effects, contact your healthcare provider.
Each Kliovance tablet contains 1 mg of estradiol and 500 mcg of norethisterone. In addition to the active ingredients, the tablets also contain excipients such as lactose monohydrate, maize starch, and magnesium stearate.
Common side effects of Kliovance may include headache, breast pain, and nausea. Serious side effects that require immediate medical attention include chest pain, unusual vaginal bleeding, and signs of a blood clot such as sudden vision changes or difficulty breathing. If you experience any severe side effects, seek medical help promptly.
Do not use Kliovance if you have a history of breast cancer, blood clots, or liver disease. Kliovance is not suitable for pregnant women or individuals with undiagnosed vaginal bleeding. If you have a history of heart disease, high blood pressure, or are taking certain medications, consult your doctor before using Kliovance. It is important to discuss your medical history and any concerns with your healthcare provider before starting Kliovance.
Brazier, Y. (2017). Hormone replacement therapy: Uses, types, and alternatives. [online] Medical News Today. Available at: https://www.medicalnewstoday.com/articles/181726.php [accessed 20 Dec 2019].
Irani, s. (2016). Menopause | Health Information | Bupa UK. [online] Bupa.co.uk. Available at: https://www.bupa.co.uk/health-information/womens-health/menopause [accessed 20 Dec 2019]. NHS UK (2017).
Menopause – Treatment. [online] nhs.uk. Available at: https://www.nhs.uk/conditions/menopause/treatment/ [accessed 20 Dec 2019].
Novo Nordisk Healthcare (2016). Kliovance – Patient Information Leaflet (PIL) – (emc). [online] Medicines.org.uk. Available at: https://www.medicines.org.uk/emc/product/1046/pil [accessed 20 Dec 2019].
Read the package leaflet before use.
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