Indivina is a medication that combines estradiol and medroxyprogesterone to help manage symptoms of menopause in women. Estradiol is a form of estrogen, while medroxyprogesterone is a progestin. These hormones work together to relieve hot flashes, night sweats, vaginal dryness, and other menopausal symptoms. Indivina is suitable for women experiencing menopausal symptoms who have not had a hysterectomy.
For Indivina, the usual starting dose is one tablet daily, taken at the same time each day. Your doctor may adjust the dosage based on your individual needs. It's important to follow your doctor's instructions carefully. If you miss a dose, take it as soon as you remember, but do not take a double dose to make up for a missed one. If you experience any unusual symptoms or have concerns about your dosage, contact your healthcare provider.
Each tablet of Indivina contains 1mg of estradiol and 2.5mg of medroxyprogesterone acetate. In addition to the active ingredients, the tablets also contain excipients such as lactose monohydrate, maize starch, talc, magnesium stearate, hypromellose, macrogol 6000, titanium dioxide (E171), and red iron oxide (E172).
Common side effects of Indivina may include headache, breast pain, nausea, and irregular vaginal bleeding. Serious side effects that require immediate medical attention include chest pain, sudden shortness of breath, severe headaches, vision changes, and signs of a blood clot (such as swelling or redness in the legs).
Do not use Indivina if you have a history of certain medical conditions like breast cancer, blood clots, or liver disease. This medication is not suitable for pregnant women or individuals with undiagnosed vaginal bleeding. If you have a history of heart disease, stroke, or are on medications like blood thinners, speak to your doctor before starting Indivina to ensure it is safe for you.
NICE, 2018, Indivina Tablets online, [accessed 19 June 2019], available on: https://bnf.nice.org.uk/clinical-medicinal- product-information/indivina-tablets.html
Orion Corporation, 2018, Indivina 1mg/5mg tablets, Online [accessed 19 June 2019], available on: https://www.medicines.org.uk/emc/product/4066/pil
Read the package leaflet before use.
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